COMP Proteine
(Cartilage Oligomeric Matrix Protein (COMP))
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].
Ergebnisse filtern:
22 Treffer
COMP
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN7866531
600,00 €
Zzgl. Versandkosten 20,00 € und MwSt
50 μg
Lieferung nach:
Deutschland
Lieferung in 6 bis 9 Werktagen
Produktnummer ABIN1061972
359,86 €
Zzgl. Versandkosten 20,00 € und MwSt
10 μg
(Weitere Mengeneinheiten)
Lieferung nach:
Deutschland
Lieferung in 10 bis 12 Werktagen
Aktuelle Publikationen für unsere COMP Proteine
: "ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas." in: FEBS open bio, Vol. 10, Issue 9, pp. 1856-1867, (2020) (PubMed).
: "Characterization of a pseudoachondroplasia-associated mutation (His587-->Arg) in the C-terminal, collagen-binding domain of cartilage oligomeric matrix protein (COMP)." in: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 479-87, (2004) (PubMed).
: "Characterization of a pseudoachondroplasia-associated mutation (His587-->Arg) in the C-terminal, collagen-binding domain of cartilage oligomeric matrix protein (COMP)." in: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 479-87, (2004) (PubMed).
Aliase für COMP Proteine
cartilage oligomeric matrix protein (COMP) Proteinecartilage oligomeric matrix protein (sce3551) Proteine
cartilage oligomeric matrix protein (CJA_1292) Proteine
cartilage oligomeric matrix protein (Comp) Proteine
COMP Proteine
EDM1 Proteine
EPD1 Proteine
MED Proteine
PSACH Proteine
THBS5 Proteine
TSP5 Proteine
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