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COMP Produkte

(Cartilage Oligomeric Matrix Protein (COMP))
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].

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Ausgewählte COMP Kategorien

COMP Antikörper

High quality antibodies with extensive validation data.

COMP ELISA Kits

Reliable ELISA kits for a wide range of species.

COMP Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene COMP Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (p), FACS
Validierungen
  • (5)
Kat. Nr. ABIN390893
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7433240
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (4)
Kat. Nr. ABIN6138864
Menge 100 μL
Datenblatt Datenblatt

Empfohlene COMP ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (5)
Kat. Nr. ABIN6720567
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6954397
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6954398
Menge 96 tests
Datenblatt Datenblatt

Empfohlene COMP Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Source
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1047991
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3091894
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3137424
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren COMP Produkten

Wang, Chen, Xiang, Wu, Tang, Ma, Zhang: "ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas." in: FEBS open bio, Vol. 10, Issue 9, pp. 1856-1867, (2020) (PubMed).

Idriss, Gamal, Gaber, El-Hakeim, Hammam, Ghandour, Abdelaziz, Goma: "Joint remodeling outcome of serum levels of Dickkopf-1 (DKK1), cartilage oligomeric matrix protein (COMP), and C-telopeptide of type II collagen (CTXII) in rheumatoid arthritis." in: Central-European journal of immunology, Vol. 45, Issue 1, pp. 73-79, (2020) (PubMed).

Zhao, Wang, Kong, Zhao: "Elevated serum cartilage oligomeric matrix protein and the metalloproteinase-ADAMTS7 levels are associated with vascular calcification in maintenance hemodialysis patients." in: Seminars in dialysis, Vol. 33, Issue 4, pp. 322-329, (2020) (PubMed).

Kothari, Sinha, Sardar, Tripathi, Girme, Adhikary, Singh, Maurya, Mishra, Hingorani, Trivedi: "Inhibition of cartilage degeneration and subchondral bone deterioration by Spinacia oleracea in human mimic of ACLT-induced osteoarthritis." in: Food & function, Vol. 11, Issue 9, pp. 8273-8285, (2020) (PubMed).

Jeong, Lee, Kim, Choi, Hwang-Bo, Kim, Kim, Ahn, Kim, Lee, Kim, Kim, Hong, Park, Cha, Choi: "Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate‑induced osteoarthritis rats." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 3841-3848, (2018) (PubMed).

Gu, Yang, Tan, Zhang, Lu, Ma: "Decreased Plasma COMP and Increased Plasma CTX-II Levels in a Chinese Pseudoachondroplasia Family with Novel COMP Mutation." in: BioMed research international, Vol. 2017, pp. 5809787, (2018) (PubMed).

Choudhary, Kothari, Tripathi, Singh, Adhikary, Ahmad, Kumar, Dev, Mishra, Shukla, Maurya, Mishra, Trivedi: "Spinacia oleracea extract attenuates disease progression and sub-chondral bone changes in monosodium iodoacetate-induced osteoarthritis in rats." in: BMC complementary and alternative medicine, Vol. 18, Issue 1, pp. 69, (2018) (PubMed).

Sun, Liu, Liu, Xu, Li, Meng, Ma, Huang, Li: "MeCP2 Regulates PTCH1 Expression Through DNA Methylation in Rheumatoid Arthritis." in: Inflammation, Vol. 40, Issue 5, pp. 1497-1508, (2018) (PubMed).

Aborehab, El Bishbishy, Refaiy, Waly: "A putative Chondroprotective role for IL-1β and MPO in herbal treatment of experimental osteoarthritis." in: BMC complementary and alternative medicine, Vol. 17, Issue 1, pp. 495, (2017) (PubMed).

Jiao, Wei, Chen, Li, Wang, Li, Guo, Zhang, Wei: "Cartilage oligomeric matrix protein and hyaluronic acid are sensitive serum biomarkers for early cartilage lesions in the knee joint." in: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, Vol. 21, Issue 2, pp. 146-51, (2016) (PubMed).

Synonyme und alternative Namen zu COMP

cartilage oligomeric matrix protein (COMP), cartilage oligomeric matrix protein (sce3551), cartilage oligomeric matrix protein (CJA_1292), cartilage oligomeric matrix protein (Comp), COMP, EDM1, EPD1, MED, PSACH, THBS5, TSP5

Bezeichner auf Proteinebene für COMP

  • cartilage oligomeric matrix protein
  • TSP5
  • cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple)
  • cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple)
  • pseudoachondroplasia (epiphyseal dysplasia 1, multiple)
  • thrombospondin-5
  • putative cartilage oligomeric matrix protein
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