Complement Factor I Produkte
(Complement Factor I (CFI))
Kategorien
This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte Complement Factor I Kategorien
Complement Factor I Antikörper
High quality antibodies with extensive validation data.
Complement Factor I ELISA Kits
Reliable ELISA kits for a wide range of species.
Complement Factor I Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Complement Factor I Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7444067
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7443707
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN516816
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Complement Factor I ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN6955036
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966038
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962758
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Complement Factor I Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7274339
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1349215
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3091355
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Complement Factor I Produkten
: "A monoclonal antibody targeting amyloid β (Aβ) restores complement factor I bioactivity: Potential implications in age-related macular degeneration and Alzheimer's disease." in: PLoS ONE, Vol. 13, Issue 5, pp. e0195751, (2018) (PubMed).: "Thrombotic microangiopathy without renal involvement: two novel mutations in complement-regulator genes." in: Journal of thrombosis and haemostasis : JTH, Vol. 14, Issue 2, pp. 340-5, (2016) (PubMed).
: "Atypical hemolytic uremic syndrome: Korean pediatric series." in: Pediatrics international : official journal of the Japan Pediatric Society, Vol. 57, Issue 3, pp. 431-8, (2015) (PubMed).
: "Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome." in: Journal of the American Society of Nephrology : JASN, Vol. 16, Issue 7, pp. 2150-5, (2005) (PubMed).
: "Atypical haemolytic uraemic syndrome and mutations in complement regulator genes." in: Springer seminars in immunopathology, Vol. 27, Issue 3, pp. 359-74, (2005) (PubMed).
: "Enrichment of early fetal-liver hemopoietic stem cells of the rat using monoclonal antibodies against the transferrin receptor, Thy-1, and MRC-OX82." in: Developmental immunology, Vol. 4, Issue 4, pp. 235-46, (1996) (PubMed).
Synonyme und alternative Namen zu Complement Factor I
complement factor I S homeolog (cfi.S), complement factor I L homeolog (cfi.L), complement factor I (CFI), complement factor I (cfi), complement component factor i (Cfi), complement factor I (Cfi), ahus3, AHUS3, c3b-ina, C3b-INA, c3bc4bi, c3bina, C3BINA, cfi, Cfi, CFI, factor I, FI, gb:ai721528, IF, kaf, KAF, MGC53615Bezeichner auf Proteinebene für Complement Factor I
- complement factor I
- I factor (complement)
- complement factor 1
- C3B/C4B inactivator
- C3b-inactivator
- Konglutinogen-activating factor
- complement component I
- complement control protein factor I
- complement factor I heavy chain
- light chain of factor I
- complement component 1
Haben Sie etwas anderes gesucht?
- Complement Factor H
- Complement Factor Bb
- Complement Factor B
- Complement Component C9b
- Complement C8
- Complement C5b
- Complement C5 Convertase
- Complement C4d
- Complement C4c
- Complement C4
- Complement C3d
- Complement C3c
- Complement C3b
- Complement C3 Convertase
- Complement C2
- Complement C1
- COMP
- COMMD9
- COMMD8
- COMMD7
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