MAPK11 Antikörper (AA 251-363)

Produktnummer ABIN969276

Dieses Anti-MAPK11-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MAPK11 in ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für MAPK11 Antikörper (AA 251-363) (ABIN969276)

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAPK11 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 4H6H6

Produktdetails anti-MAPK11 Antikörper

Bindungsspezifität: AA 251-363

Verwendungszweck: MAPK11 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of MAPK11 (aa251-363) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-MAPK11 Antikörper (ABIN969276)

Beardmore, Hinton, Eftychi, Apostolaki, Armaka, Darragh, McIlrath, Carr, Armit, Clacher, Malone, Kollias, Arthur: "Generation and characterization of p38beta (MAPK11) gene-targeted mice." in: Molecular and cellular biology, Vol. 25, Issue 23, pp. 10454-64, (2005) (PubMed).

Johnstone, Sibley, Lowen, Guilbert: "Epidermal growth factor stimulation of trophoblast differentiation requires MAPK11/14 (p38 MAP kinase) activation." in: Biology of reproduction, Vol. 73, Issue 6, pp. 1282-8, (2005) (PubMed).

Details zu MAPK11

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Andere Bezeichnung: MAPK11

Hintergrund: Mitogen-activated protein kinase 11.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

UniProt: Q15759

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteine