JAK3 Antikörper
Kurzübersicht für JAK3 Antikörper (ABIN969224)
Target
Alle JAK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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    - 
                                            Verwendungszweck
- JAK3 Antibody
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                                            Aufreinigung
- Ascitic fluid
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                                            Immunogen
- Purified recombinant fragment of human JAK3 expressed in E. Coli.
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                                            Isotyp
- IgG1
 
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                                            Applikationshinweise
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                        ELISA: 1/10000 FCM: 1/200 - 1/400 ICC: 1/200 - 1/1000 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
 
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    - 
                                            : "Jak3 expression and genomic sequence in pediatric acute lymphoblastic leukemia."    in: Leukemia & lymphoma, Vol. 43, Issue 12, pp. 2355-62, (2003)         (PubMed).        
 
 
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                                            : "Jak3 expression and genomic sequence in pediatric acute lymphoblastic leukemia."    in: Leukemia & lymphoma, Vol. 43, Issue 12, pp. 2355-62, (2003)         (PubMed).        
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    - JAK3 (Janus Kinase 3 (JAK3))
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                                            Andere Bezeichnung
- JAK3
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                                            Hintergrund
- JAK3, Janus kinase 3. It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
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                                            Molekulargewicht
- 125 kDa
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                                            Gen-ID
- 3718
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                                            UniProt
- P52333
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                                            Pathways
- JAK-STAT Signalweg, RTK Signalweg, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
 Target
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