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Cytokeratin 18 Antikörper (AA 391-483)

Name: Cytokeratin 18 Antikörper (AA 391-483)
Brand: antibodies-online
SKU: ABIN969075
Price: 631.53 EUR
Availability: InStock

KRT18 Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 4D11E4 unconjugated

Immunohistochemical analysis of paraffin-embedded human breast carcinoma (A), hepatocarcinoma (B), stomach cancer (C) and colon cancer tissue (D), showing cytoplasmic location with DAB staining using CK18 mouse mAb. (Cytokeratin 18 Antikörper (AA 391-483))

IHC

Western blot analysis using CK18 mouse mAb against Hela (1), NIH/3T3 (2), A549 (3), Jurkat (4), MCF-7(5), HepG2 (6), A431 (7), HEK293 (8) and K562 (9) cell lysate. (Cytokeratin 18 Antikörper (AA 391-483))

2 Abbildungen

(2 Referenzen)

Produktnummer ABIN969075

Datenblatt (PDF)

Target Alle Cytokeratin 18 (KRT18) Antikörper anzeigen

Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
Bindungsspezifität
25

16

15

12

12

9

8

7

7

6

6

5

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 391-483
Reaktivität
248

151

112

44

35

28

25

21

19

18

17

14

14

14

9

6

6

5

4

3

2

1

1
Human
Wirt
163

120

3

1

1
Maus
Passende Sekundärantikörper
Klonalität
151

137
Monoklonal
Konjugat
139

26

21

11

10

10

9

9

9

9

4

4

4

4

4

2

2

2

2

2

2

2

1

1
Dieser Cytokeratin 18 Antikörper ist unkonjugiert
Applikation
212

99

79

77

71

56

54

40

38

26

26

19

8

8

7

6

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung

purified

Immunogen

Purified recombinant fragment of human Cytokeratin 18 (aa391-483) expressed in E. coli.

Klon

4D11E4

Isotyp

IgG2b

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Applikationshinweise

ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

4°C, -20°C for long term storage
Cheng, Liu, Ho, Chao, Pei, Hsu, Yeh, Ho, Tsai, Lai: "The influence of plectin deficiency on stability of cytokeratin18 in hepatocellular carcinoma." in: Journal of molecular histology, Vol. 39, Issue 2, pp. 209-16, (2008) (PubMed).

Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: "Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast." in: Cancer genetics and cytogenetics, Vol. 178, Issue 2, pp. 94-103, (2007) (PubMed).
Target

Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Andere Bezeichnung

Cytokeratin 18 (KRT18 Produkte)

Synonyme

CK18 antikoerper, K18 antikoerper, Krt1-18 antikoerper, CYK18 antikoerper, DreK18 antikoerper, cb83 antikoerper, dapk1 antikoerper, sb:cb83 antikoerper, wu:fa13f02 antikoerper, wu:fb36b04 antikoerper, krt18 antikoerper, MGC64569 antikoerper, MGC75922 antikoerper, KRT18 antikoerper, CK-18-A antikoerper, K18-A antikoerper, NC-11 antikoerper, cyk18 antikoerper, k18 antikoerper, krt18-a antikoerper, krt18-b antikoerper, krt18a antikoerper, xkendob antikoerper, keratin 18 antikoerper, keratin 18, type I L homeolog antikoerper, keratin 18, type I antikoerper, keratin, type I cytoskeletal 18 antikoerper, K18, simple type I keratin antikoerper, Keratin, type I cytoskeletal 18 antikoerper, keratin 18, type I S homeolog antikoerper, Krt18 antikoerper, KRT18 antikoerper, krt18 antikoerper, krt18.L antikoerper, LOC700569 antikoerper, LOC100136778 antikoerper, k1c18 antikoerper, LOC100008885 antikoerper, krt18.S antikoerper

Hintergrund

Description: Cytokeratin 18, also known as CK18, CYK18, KRT18. Entrez Protein NP_000215. It encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Aliases: CK18, CYK18, KRT18

Molekulargewicht

48 kDa

Gen-ID

3875

HGNC

3875

Pathways

Apoptose, Caspase Kaskade in der Apoptose