CDK1 Antikörper

Produktnummer ABIN969039

Dieses Anti-CDK1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CDK1 in WB und ELISA. Geeignet für Human, Maus, Ratte und Affe. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für CDK1 Antikörper (ABIN969039)

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 5A6

Produktdetails anti-CDK1 Antikörper

Verwendungszweck: CDK1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CDK1 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-CDK1 Antikörper (ABIN969039)

Chen, Huang, Zhai, Dong, Wang, Lan: "[CDK1 expression and effects of CDK1 silencing on the malignant phenotype of glioma cells]." in: Zhonghua zhong liu za zhi [Chinese journal of oncology], Vol. 29, Issue 7, pp. 484-8, (2007) (PubMed).

Details zu CDK1

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Andere Bezeichnung: CDK1

Hintergrund: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.

Molekulargewicht: 34 kDa

Gen-ID: 983

UniProt: P06493

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA