Calnexin Antikörper

Produktnummer ABIN969000

Dieses Anti-Calnexin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Calnexin in WB, ELISA und ICC. Geeignet für Human. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für Calnexin Antikörper (ABIN969000)

Target: Calnexin (CANX)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Calnexin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Klon: 3H4A7

Produktdetails anti-Calnexin Antikörper

Verwendungszweck: Calnexin Antibody

Sequenz: CEAAEERPWL WVVYILTVAL

Aufreinigung: Ascitic fluid

Immunogen: Synthetic peptide corresponding to aa (CEAAEERPWLWVVYILTVAL) of human Calnexin, conjugated to KLH.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Calnexin Antikörper (ABIN969000)

Orlando: "The low-density lipoprotein receptor-related protein associates with calnexin, calreticulin, and protein disulfide isomerase in receptor-associated-protein-deficient fibroblasts." in: Experimental cell research, Vol. 294, Issue 1, pp. 244-53, (2004) (PubMed).

Egan, Pearson, Weiner, Rajendran, Rubin, Glöckner-Pagel, Canny, Du, Lukacs, Caplan: "Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects." in: Science (New York, N.Y.), Vol. 304, Issue 5670, pp. 600-2, (2004) (PubMed).

Oda, Hosokawa, Wada, Nagata: "EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin." in: Science (New York, N.Y.), Vol. 299, Issue 5611, pp. 1394-7, (2003) (PubMed).

Details zu Calnexin

Target: Calnexin (CANX)

Andere Bezeichnung: Calnexin

Hintergrund: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.

Molekulargewicht: 90 kDa

Gen-ID: 821

UniProt: P27824

Pathways: MAPK Signalweg, Thyroid Hormone Synthesis