Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Calnexin Antikörper (Internal Region)

CANX Reaktivität: Human, Maus, Ratte WB, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855124
  • Target Alle Calnexin (CANX) Antikörper anzeigen
    Calnexin (CANX)
    Bindungsspezifität
    • 49
    • 17
    • 14
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 118
    • 74
    • 73
    • 50
    • 34
    • 31
    • 31
    • 29
    • 29
    • 26
    • 25
    • 25
    • 22
    • 21
    • 20
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 116
    • 25
    • 7
    Kaninchen
    Klonalität
    • 113
    • 36
    Polyklonal
    Konjugat
    • 72
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Calnexin Antikörper ist unkonjugiert
    Applikation
    • 124
    • 81
    • 56
    • 56
    • 41
    • 27
    • 27
    • 25
    • 21
    • 14
    • 13
    • 9
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Huhn, Hund, Xenopus laevis, Zebrafisch (Danio rerio), Rind (Kuh)
    Kreuzreaktivität (Details)
    Chicken (91 %), Dog (94 %), Xenopus laevis (88 %), Zebrafish (82 %), Bovine (94 %)
    Produktmerkmale
    Rabbit Polyclonal antibody to Calnexin (calnexin)
    Calnexin antibody [N3C2], Internal
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Calnexin. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:10000*
    Kommentare

    Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , NIH-3T3 , PC-12 , Rat2

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.87 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • de Jong, Murphy, Mäger, Willms, Garcia-Guerra, Gitz-Francois, Lefferts, Gupta, Steenbeek, van Rheenen, El Andaloussi, Schiffelers, Wood, Vader: "A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA." in: Nature communications, Vol. 11, Issue 1, pp. 1113, (2020) (PubMed).

    Ilahibaks, Lei, Mol, Deshantri, Jiang, Schiffelers, Vader, Sluijter: "Biofabrication of Cell-Derived Nanovesicles: A Potential Alternative to Extracellular Vesicles for Regenerative Medicine." in: Cells, Vol. 8, Issue 12, (2020) (PubMed).

    Sever, Vo, Bols, Dixon: "Rainbow trout (Oncorhynchus mykiss) contain two calnexin genes which encode distinct proteins." in: Developmental and comparative immunology, Vol. 42, Issue 2, pp. 211-9, (2014) (PubMed).

  • Target
    Calnexin (CANX)
    Andere Bezeichnung
    Calnexin (CANX Produkte)
    Synonyme
    CNX antikoerper, IP90 antikoerper, P90 antikoerper, 1110069N15Rik antikoerper, AI988026 antikoerper, Cnx antikoerper, D11Ertd153e antikoerper, canx antikoerper, clgn antikoerper, clnx antikoerper, cnx antikoerper, PP90 antikoerper, zgc:63524 antikoerper, wu:fe06b12 antikoerper, CANX antikoerper, calnexin antikoerper, CalNeXin antikoerper, calnexin L homeolog antikoerper, CANX antikoerper, Canx antikoerper, cnx-1 antikoerper, canx.L antikoerper, canx antikoerper, LOC100283947 antikoerper
    Hintergrund
    This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.

    Cellular Localization: Endoplasmic reticulum membrane , Melanosome
    Molekulargewicht
    68 kDa
    Gen-ID
    821
    Pathways
    MAPK Signalweg, Thyroid Hormone Synthesis
Sie sind hier:
Kundenservice