IL1A Antikörper
Kurzübersicht für IL1A Antikörper (ABIN966392)
Target
Alle IL1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Ni-NTA purified recombinant human IL-1 alpha, expressed in E. Coli strain BL21 (DE3).
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Aufreinigung
- Antibodies are purified by protein A affinity chromatography
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Isotyp
- IgG2a
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Applikationshinweise
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Dilution: Western Blot: 1:500-1,000
ELISA: Determining optimal working dilutions by titration test. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- -20 °C
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: "Association of an interleukin 1 alpha polymorphism with Alzheimer's disease." in: Neurology, Vol. 55, Issue 4, pp. 480-3, (2000) (PubMed).
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- IL1A (Interleukin 1 alpha (IL1A))
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Andere Bezeichnung
- IL-1a
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Hintergrund
- Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
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Gen-ID
- 3552
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Pathways
- NF-kappaB Signalweg, Autophagie, Cancer Immune Checkpoints
Target
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