Der Monoklonal Anti-IL1A-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, IL1A in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
Dilution: Western Blot: 1:500-1,000 ELISA: Determining optimal working dilutions by titration test.
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Du, Dodel, Eastwood, Bales, Gao, Lohmüller, Müller, Kurz, Zimmer, Evans, Hake, Gasser, Oertel, Griffin, Paul, Farlow: "Association of an interleukin 1 alpha polymorphism with Alzheimer's disease." in: Neurology, Vol. 55, Issue 4, pp. 480-3, (2000) (PubMed).
Target
IL1A
(Interleukin 1 alpha (IL1A))
Andere Bezeichnung
IL-1a
Hintergrund
Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.