CSNK1A1 Antikörper
Kurzübersicht für CSNK1A1 Antikörper (ABIN965899)
Target
Alle CSNK1A1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Ni-NTA purified truncated recombinant CK1 expressed in E. Coli strain BL21 (DE3)
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Aufreinigung
- Crude ascites.
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Isotyp
- IgG1
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Applikationshinweise
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Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Lagerung
- -20 °C
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- CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))
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Andere Bezeichnung
- CK1
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Hintergrund
- CK1 (also designated Cytokeratin 1 or KRT1 ),with 644-amino acid protein (about 70kDa), is a member of the keratin family. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells.CK1 consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. CK1 is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.
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Gen-ID
- 1452
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Pathways
- WNT Signalweg, Hedgehog Signalweg
Target
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