CDK2 Antikörper
Kurzübersicht für CDK2 Antikörper (ABIN965843)
Target
Alle CDK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- CDK2 (Ab-160) antibody detects endogenous levels of total CDK2 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- The antiserum was produced against synthesized non-phosphopeptide derived from human CDK2 around the phosphorylation site of threonine160 (T-Y-TP-H-E).
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Applikationshinweise
- WB: 1:500~1:1000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 100ug/100ul.
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Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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: "p42, a novel cyclin-dependent kinase-activating kinase in mammalian cells." in: The Journal of biological chemistry, Vol. 279, Issue 6, pp. 4507-14, (2004) (PubMed).
: "Inhibition of cdk2 activating phosphorylation by mevastatin." in: The Journal of biological chemistry, Vol. 278, Issue 7, pp. 4840-6, (2003) (PubMed).
: "Kinetic mechanism of activation of the Cdk2/cyclin A complex. Key role of the C-lobe of the Cdk." in: The Journal of biological chemistry, Vol. 277, Issue 26, pp. 23847-53, (2002) (PubMed).
: "Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity." in: The Journal of biological chemistry, Vol. 274, Issue 13, pp. 8746-56, (1999) (PubMed).
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- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
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Andere Bezeichnung
- CDK2
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Pathways
- PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
Target
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