CDK1 Antikörper

Produktnummer ABIN965840

Es sind 3+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-CDK1 Antikörper wird verwendet zum Nachweis von CDK1 in Proben von Human, Maus, Ratte und Affe. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für CDK1 Antikörper (ABIN965840)

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Klon: 5A6

Produktdetails anti-CDK1 Antikörper

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CDK1 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-CDK1 Antikörper (ABIN965840)

McMullin: "The classification and diagnosis of erythrocytosis." in: International journal of laboratory hematology, Vol. 30, Issue 6, pp. 447-59, (2008) (PubMed).

Marash, Liberman, Henis-Korenblit, Sivan, Reem, Elroy-Stein, Kimchi: "DAP5 promotes cap-independent translation of Bcl-2 and CDK1 to facilitate cell survival during mitosis." in: Molecular cell, Vol. 30, Issue 4, pp. 447-59, (2008) (PubMed).

Maas: "The potential for the formation of the arginine biosynthetic enzymes and its masking during evolution." in: BioEssays : news and reviews in molecular, cellular and developmental biology, Vol. 29, Issue 5, pp. 484-8, (2007) (PubMed).

Details zu CDK1

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Andere Bezeichnung: CDK1

Hintergrund: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Synonyms: CDC2, CDC28A, P34CDC2, MGC111195, DKFZp686L20222, CDK1

Molekulargewicht: 34kDa

Gen-ID: 983

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA