Caspase 1 Antikörper (N-Term)
Kurzübersicht für Caspase 1 Antikörper (N-Term) (ABIN965750)
Target
Alle Caspase 1 (CASP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Aufreinigung
- Purified by antigen-specific affinity chromatography.
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Immunogen
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of fall armyworm (Spodoptera frugiperda) CASP1(Caspase-1 protein)
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Applikationshinweise
- ELISA, Western blotting: 1µg/ml for 2hrs.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- This antibody is stored in PBS, 50% glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- Caspase 1 (CASP1)
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Andere Bezeichnung
- CASP1
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Hintergrund
- CASP1(Caspase-1) is involved in the activation cascade of caspases responsible for apoptosis execution. The Caspase-1 is inhibited by the baculovirus anti-apoptotic protein p35. It cleaves p35 and nuclear immunophilin FKBP46. Caspase-1 contains a heterodimer of a 19/18 kDa (p19/18) and a 12 kDa (p12) subunit. The two subunits are derived from the precursor sequence by an autocatalytic mechanism. Caspase-1 belongs to the peptidase C14 family.
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Pathways
- Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
Target
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