ATF2 Antikörper (Activating Transcription Factor 2)

Details for Product anti-ATF2 Antibody No. ABIN965612
Antigen
  • CRE-BP1
  • CREB2
  • HB16
  • TREB7
  • CG12850
  • CG3749
  • dATF-2
  • DmelCG30420
  • CG30420
  • CHN1
  • Atf-2
  • CRE-BP
  • Creb2
  • D130078H02Rik
  • D18875
  • Tg(Gzma-Klra1)7Wum
  • mXBP
  • atf2-A
  • atf2l
  • activating transcription factor 2
  • Activating transcription factor-2
  • activating transcription factor 2 S homeolog
  • ATF2
  • Atf-2
  • Atf2
  • atf2.S
  • atf2
Reaktivität
Human, Maus, Ratte (Rattus)
737
464
421
41
33
23
23
14
14
10
9
5
5
2
2
1
1
Wirt
Kaninchen
682
35
19
3
Klonalität
Polyklonal
Konjugat
Dieser ATF2 Antikörper ist unkonjugiert
25
19
19
19
19
18
18
17
16
10
10
10
10
9
7
7
6
3
Applikation
Immunohistochemistry (IHC)
476
327
196
140
128
116
90
21
11
11
10
8
6
3
2
2
Optionen
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human ATF-2 around the phosphorylation site of threonine 69 or 51 (D-Q-TP-P-T).
Spezifität ATF-2 (Ab-69 or 51) antibody detects endogenous levels of total ATF-2 protein.
Reinigung The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Plasmids, Primers & others Plasmide, Primers & weitere ATF2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung ATF2 (ATF2 Antibody Abstract)
Pathways MAPK Signalweg, RTK Signalweg, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
Applikations-hinweise WB: 1:500~1:1000
IHC: 1:50~1:100.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 100ug/100ul
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Produkt verwendet in: Sevilla, Santos, Vega, Lazo: "Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK." in: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27458-65, 2004 (PubMed).

Alsayed, Uddin, Mahmud, Lekmine, Kalvakolanu, Minucci, Bokoch, Platanias: "Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid." in: The Journal of biological chemistry, Vol. 276, Issue 6, pp. 4012-9, 2001 (PubMed).

Gupta, Campbell, Dérijard, Davis: "Transcription factor ATF2 regulation by the JNK signal transduction pathway." in: Science (New York, N.Y.), Vol. 267, Issue 5196, pp. 389-93, 1995 (PubMed).

van Dam, Wilhelm, Herr, Steffen, Herrlich, Angel: "ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents." in: The EMBO journal, Vol. 14, Issue 8, pp. 1798-811, 1995 (PubMed).

Abdel-Hafiz, Heasley, Kyriakis, Avruch, Kroll, Johnson, Hoeffler: "Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases." in: Molecular endocrinology (Baltimore, Md.), Vol. 6, Issue 12, pp. 2079-89, 1993 (PubMed).

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