UBE2D2 Antikörper (C-Term)

Produktnummer ABIN955424

Produktdetails anti-UBE2D2 Antikörper

Target: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Bindungsspezifität: AA 111-140, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2D2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects UBE2D2 (C-term).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human UBE2D2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Details zu UBE2D2

Target: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Andere Bezeichnung: UBE2D2 (UBE2D2 Produkte)

Synonyme: E2(17)KB2 antikoerper, PUBC1 antikoerper, UBC4 antikoerper, UBC4/5 antikoerper, UBCH5B antikoerper, 1500034D03Rik antikoerper, Ubc2e antikoerper, Ube2d2 antikoerper, ubc4 antikoerper, ube2d2 antikoerper, zgc:55886 antikoerper, E217kB antikoerper, ubiquitin conjugating enzyme E2 D2 antikoerper, ubiquitin-conjugating enzyme E2D 2A antikoerper, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) antikoerper, ubiquitin-conjugating enzyme E2D 2 antikoerper, ubiquitin conjugating enzyme E2 D3 antikoerper, UBE2D2 antikoerper, Ube2d2a antikoerper, ube2d2 antikoerper, Ube2d2 antikoerper, UBE2D3 antikoerper

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.Synonyms: E2(17)KB 2, UBC4, UBCH5B, Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin-conjugating enzyme E2-17 kDa 2, Ubiquitin-protein ligase D2

Gen-ID: 7322

NCBI Accession: NP_003330

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades