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STIM1 Antikörper (C-Term)
STIM1
Reaktivität: Human
WB, IHC (p), EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-STIM1 Antikörper
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Target
Alle STIM1 Antikörper anzeigen
STIM1
(Stromal Interaction Molecule 1 (STIM1))
Bindungsspezifität
Alle Epitope für STIM1 Antikörper
AA 516-546, C-Term
Reaktivität
Alle Reaktivitäten für STIM1 Antikörper
Human
Wirt
Alle Wirte für STIM1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für STIM1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für STIM1 Antikörper
Dieser STIM1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für STIM1 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Spezifität
This antibody reacts to STIM1.
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Aufreinigung
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 516-546 amino acids from the C-terminal region of human STIM1
Isotyp
Ig Fraction
Top Product
Discover our top product STIM1 Primärantikörper
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anti-Stromal Interaction Molecule 1 (STIM1) (AA 56-69), (Extracellular), (N-Term) antibody
STIM1
Reaktivität: Human, Ratte, Maus
WB, IHC, IP, IF, ICC, FACS, LCI
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu STIM1
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Target
STIM1
(Stromal Interaction Molecule 1 (STIM1))
Andere Bezeichnung
STIM1 / GOK (STIM1 Produkte )
Synonyme
stim1 antikoerper, MGC76045 antikoerper, STIM1 antikoerper, si:dkey-24p1.5 antikoerper, MGC154748 antikoerper, si:ch211-112l17.2 antikoerper, Stim1 antikoerper, D11S4896E antikoerper, GOK antikoerper, TAM antikoerper, SIM antikoerper, stromal interaction molecule 1 antikoerper, stromal interaction molecule 1a antikoerper, stromal interaction molecule 1 L homeolog antikoerper, stromal interaction molecule 1b antikoerper, STIM1 antikoerper, stim1 antikoerper, stim1a antikoerper, stim1.L antikoerper, stim1b antikoerper, Stim1 antikoerper
Hintergrund
This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene.Synonyms: Stromal interaction molecule 1
Molekulargewicht
77423 Da
Gen-ID
6786
NCBI Accession
NP_003147
Pathways
T-Zell Rezeptor Signalweg , BCR Signaling
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