STIM1 Antikörper (AA 2-350)
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- Target Alle STIM1 Antikörper anzeigen
- STIM1 (Stromal Interaction Molecule 1 (STIM1))
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Bindungsspezifität
- AA 2-350
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser STIM1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Stromal interaction molecule 1 protein (2-350AA)
- Isotyp
- IgG
- Top Product
- Discover our top product STIM1 Primärantikörper
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anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-685) antibody
STIM1 Reaktivität: Human WB, ELISA, IHC (p), IF Wirt: Maus Monoclonal 5A2 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 1-211) antibodySTIM1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (C-Term) antibodySTIM1 Reaktivität: Human, Ratte, Maus WB, IP, IHC (p), ICC Wirt: Maus Monoclonal CDN3H4 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-686) antibodySTIM1 Reaktivität: Human WB, IHC (p), IF, EIA Wirt: Maus Monoclonal 5A2 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 509-538), (C-Term) antibodySTIM1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB19222 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (C-Term) antibodySTIM1 Reaktivität: Human, Ratte, Maus WB, IP, IHC (p), IF, ICC Wirt: Maus Monoclonal CDN3H4 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 24-686) antibodySTIM1 Reaktivität: Human WB, ELISA, IHC, IHC (p), IF Wirt: Maus Monoclonal 5A2 unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 25-139) antibodySTIM1 Reaktivität: Human, Ratte, Maus WB, IF Wirt: Maus Monoclonal 44-GOK unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 45-74), (N-Term) antibodySTIM1 Reaktivität: Human, Ratte, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Stromal Interaction Molecule 1 (STIM1) (AA 56-69), (Extracellular), (N-Term) antibodySTIM1 Reaktivität: Human, Ratte, Maus WB, IHC, IP, IF, ICC, FACS, LCI Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- STIM1 (Stromal Interaction Molecule 1 (STIM1))
- Andere Bezeichnung
- STIM1 (STIM1 Produkte)
- Synonyme
- stim1 antikoerper, MGC76045 antikoerper, STIM1 antikoerper, si:dkey-24p1.5 antikoerper, MGC154748 antikoerper, si:ch211-112l17.2 antikoerper, Stim1 antikoerper, D11S4896E antikoerper, GOK antikoerper, TAM antikoerper, SIM antikoerper, stromal interaction molecule 1 antikoerper, stromal interaction molecule 1a antikoerper, stromal interaction molecule 1 L homeolog antikoerper, stromal interaction molecule 1b antikoerper, STIM1 antikoerper, stim1 antikoerper, stim1a antikoerper, stim1.L antikoerper, stim1b antikoerper, Stim1 antikoerper
- Hintergrund
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Background: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:15866891, PubMed:16005298, PubMed:16208375, PubMed:16537481, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:18854159, PubMed:19249086, PubMed:22464749, PubMed:24069340, PubMed:24351972, PubMed:24591628, PubMed:26322679, PubMed:25326555). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 (PubMed:16208375, PubMed:16537481). Involved in enamel formation (PubMed:24621671). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch (PubMed:26322679).
Aliases: D11S4896E antibody, GOK antibody, OTTHUMP00000164512 antibody, OTTHUMP00000229140 antibody, OTTHUMP00000230742 antibody, SIM antibody, STIM 1 antibody, STIM1 antibody, Stim1 stromal interaction molecule 1 antibody, STIM1_HUMAN antibody, STIM1L antibody, Stromal interaction molecule 1 antibody
- UniProt
- Q13586
- Pathways
- T-Zell Rezeptor Signalweg, BCR Signaling
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