PDHA1 Antikörper (Middle Region)

Produktnummer ABIN954070

Produktdetails anti-PDHA1 Antikörper

Target: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Bindungsspezifität: AA 233-263, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDHA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human PDHA1 (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 233~263 amino acids from the Central region of Human PDHA1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PDHA1

Target: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Andere Bezeichnung: PDHA1 (PDHA1 Produkte)

Synonyme: PDHA antikoerper, PDHCE1A antikoerper, PHE1A antikoerper, Pdha-1 antikoerper, pdha antikoerper, phe1a antikoerper, pdhce1a antikoerper, im:6895726 antikoerper, pdha1 antikoerper, wu:fd18b01 antikoerper, wu:fo96f03 antikoerper, zgc:73271 antikoerper, zgc:86692 antikoerper, Pdha1 antikoerper, wu:fp73b04 antikoerper, zgc:92705 antikoerper, NI36_05250 antikoerper, pdha1-a antikoerper, pdha1-b antikoerper, pyruvate dehydrogenase E1 alpha 1 subunit antikoerper, pyruvate dehydrogenase E1 alpha 1 antikoerper, pyruvate dehydrogenase (lipoamide) alpha 1 antikoerper, pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene antikoerper, 2-oxo acid dehydrogenase antikoerper, pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha antikoerper, pyruvate dehydrogenase alpha subunit protein antikoerper, pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit antikoerper, precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit antikoerper, pyruvate dehydrogenase antikoerper, pyruvate dehydrogenase E1 alpha 1 subunit a antikoerper, pyruvate dehydrogenase E1 alpha 1 subunit b antikoerper, pyruvate dehydrogenase E1 component subunit alpha antikoerper, pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog antikoerper, PDHA1 antikoerper, Pdha1 antikoerper, pdha1 antikoerper, LOC719277 antikoerper, VNG_RS07485 antikoerper, RR_RS04695 antikoerper, pdhA1 antikoerper, pdha1a antikoerper, pdha1b antikoerper, NI36_RS05240 antikoerper, pdha1.S antikoerper

Hintergrund: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome.Synonyms: PDHE1-A type I, PHE1A, Pyruvate dehydrogenase E1 component subunit alpha somatic form mitochondrial

Molekulargewicht: 43296 Da

Gen-ID: 5160

NCBI Accession: NP_000275

Pathways: Warburg Effekt