NEIL1 Antikörper (Middle Region)
Kurzübersicht für NEIL1 Antikörper (Middle Region) (ABIN953643)
Target
Alle NEIL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 137-167, Middle Region
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Spezifität
- This antibody recognizes Human NEIL1 (Center).
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Aufreinigung
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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Immunogen
- KLH conjugated synthetic peptide between 137~167 amino acids from the Central region of human NEIL1
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
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Andere Bezeichnung
- NEIL1
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Hintergrund
- NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).Synonyms: DNA glycosylase/AP lyase Neil1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Endonuclease VIII-like 1, FPG1, NEH1
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Molekulargewicht
- 43684 Da
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Gen-ID
- 79661
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NCBI Accession
- NP_078884
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Pathways
- DNA Reparatur
Target
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