EPAS1 Antikörper (N-Term)

Produktnummer ABIN952733

Der Kaninchen Polyklonal Anti-EPAS1-Antikörper wurde für WB, FACS und EIA validiert. Er ist geeignet, EPAS1 in Proben von Human zu detektieren.

Kurzübersicht für EPAS1 Antikörper (N-Term) (ABIN952733)

Target: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPAS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Produktdetails anti-EPAS1 Antikörper

Bindungsspezifität: AA 127-154, N-Term

Spezifität: This antibody recognizes Human HIF2A / HIF2 alpha (N-term).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 127-154 amino acids from the N-terminal region of Human HIF2A Genename: EPAS1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu EPAS1

Target: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Andere Bezeichnung: HIF2A / HIF2 alpha

Hintergrund: This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.Synonyms: BHLHE73, Basic-helix-loop-helix-PAS protein MOP2, Class E basic helix-loop-helix protein 73, EPAS1, Endothelial PAS domain-containing protein 1, HIF-1 alpha-like factor, HIF-2 alpha, HIF-related factor, HLF, Hypoxia-inducible factor 2 alpha, MOP2, PASD2

Molekulargewicht: 96459 Da

Gen-ID: 2034

NCBI Accession: NP_001421

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effekt