TRAIL Antikörper

Produktnummer ABIN933806

Produktdetails anti-TRAIL Antikörper

Target: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TRAIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Immunogen: TRAIL antibody was raised in mouse using highly pure recombinant human TRAIL/APO-II as the immunogen.

Klon: M912292

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: ELISA: 2-4 µg/mL, Inhibition: 0.3-0.6 µg/mL, WB: 0.25-0.5 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from PBS.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu TRAIL

Target: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Andere Bezeichnung: TRAIL (TNFSF10 Produkte)

Synonyme: APO2L antikoerper, Apo-2L antikoerper, CD253 antikoerper, TL2 antikoerper, TRAIL antikoerper, A330042I21Rik antikoerper, AI448571 antikoerper, APO-2L antikoerper, Ly81 antikoerper, Trail antikoerper, tl2 antikoerper, apo2l antikoerper, cd253 antikoerper, trail antikoerper, apo-2l antikoerper, trail1 antikoerper, xtrail1 antikoerper, tnfsf10l2 antikoerper, zgc:92320 antikoerper, TNLG6A antikoerper, TNF superfamily member 10 antikoerper, tumor necrosis factor (ligand) superfamily, member 10 antikoerper, tumor necrosis factor superfamily member 10 antikoerper, TNF superfamily member 10 S homeolog antikoerper, TNFSF10 antikoerper, Tnfsf10 antikoerper, tnfsf10.S antikoerper, tnfsf10 antikoerper

Hintergrund: TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic “death domain”, which activates the cell’s apoptotic machinery. Synonyms: Monoclonal TRAIL antibody, Anti-TRAIL antibody, TNF-related apoptosis-inducing Ligand antibody, TNFSF10 antibody, TL2 antibody.

Molekulargewicht: 20.0 kDa (predicted detection band MW)

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity