TRAIL Antikörper

Produktnummer ABIN933806

Der Maus Monoklonal Anti-TRAIL-Antikörper wurde für WB, ELISA und Inhibition validiert. Er ist geeignet, TRAIL in Proben von Human zu detektieren.

Kurzübersicht für TRAIL Antikörper (ABIN933806)

Target: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TRAIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Klon: M912292

Produktdetails anti-TRAIL Antikörper

Immunogen: TRAIL antibody was raised in mouse using highly pure recombinant human TRAIL/APO-II as the immunogen.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: ELISA: 2-4 µg/mL, Inhibition: 0.3-0.6 µg/mL, WB: 0.25-0.5 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from PBS.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu TRAIL

Target: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Andere Bezeichnung: TRAIL

Hintergrund: TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic “death domain”, which activates the cell’s apoptotic machinery. Synonyms: Monoclonal TRAIL antibody, Anti-TRAIL antibody, TNF-related apoptosis-inducing Ligand antibody, TNFSF10 antibody, TL2 antibody.

Molekulargewicht: 20.0 kDa (predicted detection band MW)

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity