ORC6 Antikörper

Produktnummer ABIN931160

Der Maus Monoklonal anti-ORC6 Antikörper wird verwendet zum Nachweis von ORC6 in Proben von Human. Er wurde validiert für DB und ICC.

Kurzübersicht für ORC6 Antikörper (ABIN931160)

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ORC6 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB), Immunocytochemistry (ICC)

Klon: 2679C2b

Produktdetails anti-ORC6 Antikörper

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: ORC6 L antibody was raised in mouse using recombinant Human Origin Recognition Complex, Subunit 6 Like (Yeast) (Orc6 )

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: ORC6 L antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu ORC6

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Andere Bezeichnung: ORC6L

Hintergrund: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. Synonyms: Monoclonal ORC6L antibody, Anti-ORC6L antibody, Origin recognition complex subunit 6 antibody, ORC6 antibody.

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA