ORC6 Antikörper (C-Term)

Produktnummer ABIN2855901

Produktdetails anti-ORC6 Antikörper

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to ORC6L (origin recognition complex, subunit 6 like (yeast))
ORC6L antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ORC6. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Molt-4

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu ORC6

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Andere Bezeichnung: origin recognition complex subunit 6 (ORC6 Produkte)

Synonyme: Orc6l antikoerper, CG1584 antikoerper, DmORC 6 antikoerper, DmORC6 antikoerper, Dmel\\CG1584 antikoerper, ORC antikoerper, ORC6 antikoerper, orc6 antikoerper, rDmORC antikoerper, ORC6L antikoerper, ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6 antikoerper, ATORC6 antikoerper, ORIGIN RECOGNITION COMPLEX SUBUNIT 6 antikoerper, T2P11.3 antikoerper, T2P11_3 antikoerper, origin recognition complex protein 6 antikoerper, DDBDRAFT_0186183 antikoerper, DDBDRAFT_0233113 antikoerper, DDB_0186183 antikoerper, DDB_0233113 antikoerper, LOC100284755 antikoerper, orc6l antikoerper, 6720420I10Rik antikoerper, origin recognition complex, subunit 6 antikoerper, Origin recognition complex subunit 6 antikoerper, origin recognition complex subunit 6 antikoerper, origin recognition complex protein 6 antikoerper, origin recognition complex subunit Orc6 antikoerper, Orc6 antikoerper, ORC6 antikoerper, CpipJ_CPIJ005016 antikoerper, SJAG_01267 antikoerper, orcF antikoerper, LOC100284755 antikoerper, orc6 antikoerper

Hintergrund: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

Cellular Localization: Nucleus

Molekulargewicht: 28 kDa

Gen-ID: 23594

UniProt: Q9Y5N6

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA