ORC6 Antikörper (AA 160-240)

Produktnummer ABIN7230410

Der Kaninchen Polyklonal anti-ORC6 Antikörper wird verwendet zum Nachweis von ORC6 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für ORC6 Antikörper (AA 160-240) (ABIN7230410)

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ORC6 Antikörper

Bindungsspezifität: AA 160-240

Verwendungszweck: Rabbit Anti-ORC6 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of ORC6 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ORC6 protein at AA range: 160-240

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ORC6

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Andere Bezeichnung: ORC6

Hintergrund: Origin recognition complex subunit 6The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by ORC6 is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

Molekulargewicht: 27kD

Gen-ID: 23594

UniProt: Q9Y5N6

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA