Caspase 6 Antikörper (Middle Region)

Produktnummer ABIN929109

Der Kaninchen Polyklonal anti-Caspase 6 Antikörper (ABIN929109) detektiert spezifisch Caspase 6 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Caspase 6 Antikörper (Middle Region) (ABIN929109)

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Caspase 6 Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: CASP6 antibody was raised in rabbit using the middle region of CASP6 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CASP6 Blocking Peptide, (ABIN5612634), is also available for use as a blocking control in assays to test for specificity of this CASP6 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Andere Bezeichnung: CASP6

Hintergrund: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. Synonyms: Polyclonal CASP6 antibody, Anti-CASP6 antibody, caspase 6, apoptosis-related cysteine peptidase antibody, MCH2 antibody.

Pathways: Apoptose, Caspase Kaskade in der Apoptose