RAD51 Homolog B Antikörper (Middle Region)

Produktnummer ABIN928985

Der Kaninchen Polyklonal Anti-RAD51 Homolog B-Antikörper wurde für WB validiert. Er ist geeignet, RAD51 Homolog B in Proben von Human zu detektieren.

Kurzübersicht für RAD51 Homolog B Antikörper (Middle Region) (ABIN928985)

Target: RAD51 Homolog B (Rad51B)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD51 Homolog B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RAD51 Homolog B Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: RAD51 L1 antibody was raised in rabbit using the middle region of RAD51 1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

RAD51L1 Blocking Peptide, (ABIN939488), is also available for use as a blocking control in assays to test for specificity of this RAD51L1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu RAD51 Homolog B

Target: RAD51 Homolog B (Rad51B)

Andere Bezeichnung: RAD51L1

Hintergrund: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Synonyms: Polyclonal RAD51L1 antibody, Anti-RAD51L1 antibody, RAD51-like 1, S. cerevisiae antibody, MGC34245 antibody, R51H2 antibody, RAD51B antibody, REC2 antibody, hREC2 antibody.

Pathways: DNA Reparatur