STAT5B Antikörper (N-Term)

Produktnummer ABIN927756

Der Kaninchen Polyklonal anti-STAT5B Antikörper (ABIN927756) detektiert spezifisch STAT5B in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Zebrafisch (Danio rerio), Huhn und Xenopus laevis.

Kurzübersicht für STAT5B Antikörper (N-Term) (ABIN927756)

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Zebrafisch (Danio rerio), Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAT5B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-STAT5B Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Huhn, Schwein, Rind (Kuh), Hund, Zebrafisch (Brachydanio rerio), Frosch

Aufreinigung: Purified

Immunogen: STAT5 B antibody was raised in rabbit using the N terminal of STAT5 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

STAT5B Blocking Peptide, (ABIN937008), is also available for use as a blocking control in assays to test for specificity of this STAT5B antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu STAT5B

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Andere Bezeichnung: STAT5B

Hintergrund: The protein is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. Synonyms: Polyclonal STAT5B antibody, Anti-STAT5B antibody, signal transducer and activator of transcription 5B antibody, STAT5 antibody.

Pathways: JAK-STAT Signalweg, RTK Signalweg, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation