FGD1 Antikörper (N-Term)

Produktnummer ABIN927716

Der Kaninchen Polyklonal Anti-FGD1-Antikörper wurde für WB validiert. Er ist geeignet, FGD1 in Proben von Human, Rind (Kuh) und Hund zu detektieren.

Kurzübersicht für FGD1 Antikörper (N-Term) (ABIN927716)

Target: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Reaktivität: Human, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FGD1 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Rind (Kuh), Hund

Aufreinigung: Purified

Immunogen: FGD1 antibody was raised in rabbit using the N terminal of FGD1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

FGD1 Blocking Peptide, (ABIN939123), is also available for use as a blocking control in assays to test for specificity of this FGD1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu FGD1

Target: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Andere Bezeichnung: FGD1

Hintergrund: FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. Synonyms: Polyclonal FGD1 antibody, Anti-FGD1 antibody, FYVE, RhoGEF and PH domain containing 1, faciogenital dysplasia antibody, AAS antibody, FGDY antibody, ZFYVE3 antibody.

Pathways: Neurotrophin Signalübertragung