FGD1 Antikörper (C-Term)

Produktnummer ABIN2777407

Der Kaninchen Polyklonal anti-FGD1 Antikörper (ABIN2777407) detektiert spezifisch FGD1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Rind (Kuh), Hund, Schwein, Ratte, Maus, Kaninchen und Pferd.

Kurzübersicht für FGD1 Antikörper (C-Term) (ABIN2777407)

Target: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Reaktivität: Human, Rind (Kuh), Hund, Schwein, Ratte, Maus, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FGD1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: FGD1 Antibody - C-terminal region

Sequenz: WMAVLGRAGR GDTFCPGPTL SEDREMEEAP VAALGATAEP PESPQTRDKT

Homologie: Cow: 86%, Dog: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against FGD1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FGD1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31673-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FGD1

Target: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Andere Bezeichnung: FGD1

Hintergrund:

Background Information: FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.

Gene Name: FYVE, RhoGEF and PH domain containing 1

Alternative Symbols: AAS, FGDY, MRXS16, ZFYVE3

Protein Name: FYVE, RhoGEF and PH domain-containing protein 1

Molekulargewicht: 107kDa

Gen-ID: 2245

NCBI Accession: NP_004454

UniProt: P98174

Pathways: Neurotrophin Signalübertragung