FGD1 Antikörper (AA 700-800)

Produktnummer ABIN7267284

Produktdetails anti-FGD1 Antikörper

Target: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Bindungsspezifität: AA 700-800

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: FGD1 Rabbit pAb

Sequenz: LLNSTNREDE DTPPNSPNVD LGKRAPTPIR EKEVTMCMRC QEPFNSITKR RHHCKACGHV VCGKCSEFRA RLVYDNNRSN RVCTDCYVAL HGVPGSSPAC S

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FGD1 (NP_004454.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FGD1

Target: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Andere Bezeichnung: FGD1 (FGD1 Produkte)

Synonyme: AAS antikoerper, FGDY antikoerper, MRXS16 antikoerper, ZFYVE3 antikoerper, FYVE, RhoGEF and PH domain containing 1 antikoerper, FGD1 antikoerper, Fgd1 antikoerper, fgd1 antikoerper

Hintergrund: This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.,FGD1,AAS,FGDY,MRXS16,ZFYVE3,FYVE,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,FGD1

Molekulargewicht: 106kDa

Gen-ID: 2245

UniProt: P98174

Pathways: Neurotrophin Signalübertragung