Caspase 3 Antikörper (N-Term)

Produktnummer ABIN925983

Dieses Anti-Caspase 3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Caspase 3 in WB und IHC. Geeignet für Human, Ratte, Rind (Kuh), Hund, Kaninchen und Schwein.

Kurzübersicht für Caspase 3 Antikörper (N-Term) (ABIN925983)

Target: Caspase 3 (CASP3)

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Caspase 3 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Ratte (Rattus), Schwein, Hund, Kaninchen, Rind (Kuh)

Immunogen: CASP3 antibody was raised in rabbit using the N terminal of CASP3 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 5 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CASP3 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CASP3 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Caspase 3

Target: Caspase 3 (CASP3)

Andere Bezeichnung: CASP3

Hintergrund: CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. Synonyms: Polyclonal CASP3 antibody, Anti-CASP3 antibody, caspase 3, apoptosis-related cysteine peptidase antibody.

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation