MAPK11 Antikörper (AA 21-120) (AbBy Fluor® 488)

Produktnummer ABIN905666

Der Kaninchen-Polyklonal Anti-MAPK11-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet zum Nachweis von MAPK11 in Proben aus Ratte. }

Kurzübersicht für MAPK11 Antikörper (AA 21-120) (AbBy Fluor® 488) (ABIN905666)

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK11 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-MAPK11 Antikörper (AbBy Fluor® 488)

Bindungsspezifität: AA 21-120

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAPK11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MAPK11

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Andere Bezeichnung: MAPK11

Hintergrund:

Synonyms: P38B, SAPK2, p38-2, PRKM11, SAPK2B, p38Beta, P38BETA2, Mitogen-activated protein kinase 11, MAP kinase 11, MAPK 11, Mitogen-activated protein kinase p38 beta, MAP kinase p38 beta, Stress-activated protein kinase 2b, MAPK11

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK11 is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

Gen-ID: 5600

UniProt: Q15759

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteine