CRHR1 Antikörper (AbBy Fluor® 350)

Produktnummer ABIN892253

Der Kaninchen Polyklonal anti-CRHR1 Antikörper wird verwendet zum Nachweis von CRHR1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und IF (p).

Kurzübersicht für CRHR1 Antikörper (AbBy Fluor® 350) (ABIN892253)

Target: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRHR1 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CRHR1 Antikörper (AbBy Fluor® 350)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRHR1/CRFR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CRHR1

Target: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Andere Bezeichnung: CRHR1

Hintergrund:

Synonyms: Corticotropin releasing hormone receptor variant 1h,CRF-RI, CRF 1, CRF R, CRF1, CRFR1, CRH R1h, CRF-R1, CRHR 1, CRHR, CRHR1, CRHR1f, Releasing hormone receptor 1, Seven transmembrane helix receptor, corticotropin releasing hormone receptor 1, Crhr1, Crhr, MGC124237, MGC124240, CRF-R, CRF-R-1, CRF-R1, CRFR-1, CRH-R-1, CRH-R1, CRH-R1h, CRHR, CRHR1L, CRFR1_HUMAN.

Background: This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants one of which is a non-coding read-through transcript with the neighboring gene MGC57346.

Molekulargewicht: 48kDa

Gen-ID: 1394

Pathways: Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity