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PARP3 Antikörper (AA 301-400)

Der Kaninchen Polyklonal Anti-PARP3-Antikörper wurde für ELISA, WB, IF (cc), IF (p), IHC (p) und IHC (fro) validiert. Er ist geeignet, PARP3 in Proben von Maus zu detektieren.
Produktnummer ABIN873020

Kurzübersicht für PARP3 Antikörper (AA 301-400) (ABIN873020)

Target

Alle PARP3 Antikörper anzeigen
PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Reaktivität

  • 35
  • 25
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Maus

Wirt

  • 46
  • 3
  • 1
Kaninchen

Klonalität

  • 49
  • 1
Polyklonal

Konjugat

  • 27
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PARP3 Antikörper ist unkonjugiert

Applikation

  • 36
  • 18
  • 15
  • 12
  • 12
  • 9
  • 3
  • 2
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400

    Kreuzreaktivität

    Maus

    Homologie

    Human,Rat,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human PARP3

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

    Andere Bezeichnung

    PARP3

    Hintergrund

    Synonyms: hPARP3, IRT1, NAD+ ADP ribosyltransferase 3, pADPRT 3, Poly[ADP ribose] synthetase 3, ADP ribosyltransferase NAD+, poly ADP ribose, ADPRT-3, ADPRT3, ADPRTL2, ADPRTL3, hPARP 3, hPARP-3, IRT 1, IRT1, NAD+ ADP-ribosyltransferase 3, NAD+ ADP ribosyltransferase 3, pADPRT-3, pADPRT3, PARP 3, PARP-3, PARP3, Poly ADP ribose polymerase family, member 3, Poly ADP ribose synthetase 3, Poly [ADP-ribose] polymerase 3, Poly[ADP-ribose] synthase 3.

    Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.Tissue specificity: Widely expressed, the highest levels are in the kidney, skeletal muscle, liver, heart and spleen, also detected in pancreas, lung, placenta, brain, leukocytes, colon, small intestine, ovary, testis, prostate and thymus.

    Gen-ID

    10039
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