Der Maus Monoklonal anti-MAP2K6 Antikörper wird verwendet zum Nachweis von MAP2K6 in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IHC und FACS.
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Lagerung
4 °C
Target
MAP2K6
(Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
Andere Bezeichnung
MAP2K6
Hintergrund
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas . Synonyms: MEK6, MKK6, MAPKK6, PRKMK6, SAPKK3, MAP2K6