Cyclin D3 Antikörper

Produktnummer ABIN865425

Der Maus Monoklonal anti-Cyclin D3 Antikörper (Klon 6H4) (ABIN865425) detektiert spezifisch Cyclin D3 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Cyclin D3 Antikörper (ABIN865425)

Target: Cyclin D3 (CCND3)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cyclin D3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 6H4

Produktdetails anti-Cyclin D3 Antikörper

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CCND3 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100g/100l

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu Cyclin D3

Target: Cyclin D3 (CCND3)

Andere Bezeichnung: CCND3

Hintergrund: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. Synonyms: CCND3

Molekulargewicht: 32kDa

Gen-ID: 896

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process