Cyclin D3 Antikörper (C-Term)
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- Target Alle Cyclin D3 (CCND3) Antikörper anzeigen
- Cyclin D3 (CCND3)
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Bindungsspezifität
- AA 252-281, C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cyclin D3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- B
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This CCND3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from the C-terminal region of human CCND3.
- Klon
- RB43029
- Isotyp
- Ig Fraction
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anti-Cyclin D3 (CCND3) (AA 1-292) antibody
CCND3 Reaktivität: Human WB, ELISA, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
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anti-Cyclin D3 (CCND3) (pThr283) antibodyCCND3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 136-292) antibodyCCND3 Reaktivität: Human, Ratte WB, FACS Wirt: Kaninchen Polyclonal unconjugated
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anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 Reaktivität: Human WB, IHC (p), IF Wirt: Maus Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (C-Term) antibodyCCND3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Schaf, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 Reaktivität: Human WB, ELISA, IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cyclin D3 (CCND3) antibodyCCND3 Reaktivität: Human WB Wirt: Kaninchen Monoclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 33-66), (N-Term) antibodyCCND3 Reaktivität: Ratte WB Wirt: Kaninchen Polyclonal RB43404 unconjugated
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- Applikationshinweise
- WB: 1:1000. WB: 1:1000. IHC-P: 1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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- Target
- Cyclin D3 (CCND3)
- Andere Bezeichnung
- CCND3 (CCND3 Produkte)
- Synonyme
- zgc:103502 antikoerper, CCND3 antikoerper, 9230106B05Rik antikoerper, AA682053 antikoerper, AL024085 antikoerper, AW146355 antikoerper, C78795 antikoerper, cyclin D3 antikoerper, ccnd3 antikoerper, CCND3 antikoerper, Ccnd3 antikoerper
- Hintergrund
- Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
- Molekulargewicht
- 32520
- NCBI Accession
- NP_001129489, NP_001129597, NP_001129598, NP_001751
- UniProt
- P30281
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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