Cytokeratin 18 Antikörper (pSer60) (Cy5.5)

Produktnummer ABIN801593

Der Kaninchen Polyklonal Anti-Cytokeratin 18-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, Cytokeratin 18 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Cytokeratin 18 Antikörper (pSer60) (Cy5.5) (ABIN801593)

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cytokeratin 18 Antikörper ist konjugiert mit Cy5.5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Cytokeratin 18 Antikörper (Cy5.5)

Bindungsspezifität: pSer60

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human CK18 around the phosphorylation site of Ser60 [MG(p-S)GG]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Cytokeratin 18

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Andere Bezeichnung: CK18

Hintergrund:

Synonyms: Cytokeratin 18 phospho S60, p-Cytokeratin 18 phospho S60, Cell proliferation inducing gene 46 protein, Cell proliferation inducing protein 46, Cell proliferation-inducing gene 46 protein, CK 18, CK-18, CK18, CYK 18, CYK18, Cytokeratin 18, Cytokeratin endo B, Cytokeratin-18, Cytokeratin18, K 18, K18, K1C18_HUMAN, Keratin 18, Keratin D, Keratin type I cytoskeletal 18, keratin, type I cytoskeletal 18, Keratin-18, Keratin18, Kerd, KRT18.

Background: KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

Gen-ID: 3875

Pathways: Apoptose, Caspase Kaskade in der Apoptose