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MCL-1 Antikörper (AA 121-139)
MCL1
Reaktivität: Human
IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-MCL-1 Antikörper
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Target
Alle MCL-1 (MCL1) Antikörper anzeigen
MCL-1 (MCL1)
(Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
Bindungsspezifität
Alle Epitope für MCL-1 Antikörper
AA 121-139
Reaktivität
Alle Reaktivitäten für MCL-1 Antikörper
Human
Wirt
Alle Wirte für MCL-1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für MCL-1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für MCL-1 Antikörper
Dieser MCL-1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für MCL-1 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This antibody reacts to Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1).
Aufreinigung
Immunoaffinity Chromatography
Immunogen
A synthetic peptide corresponding to aa 121-139 of human Mcl-1 Genename: MCL1
Isotyp
IgG
Top Product
Discover our top product MCL1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
10 mM PBS, pH 7.4 containing 1 % BSA as stabilizer and 0,09 % sodium azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Details zu MCL-1
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Target
MCL-1 (MCL1)
(Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
Andere Bezeichnung
MCL1 (MCL1 Produkte )
Synonyme
BCL2L3 antikoerper, EAT antikoerper, MCL1-ES antikoerper, MCL1L antikoerper, MCL1S antikoerper, Mcl-1 antikoerper, TM antikoerper, bcl2-L-3 antikoerper, mcl1/EAT antikoerper, AW556805 antikoerper, mcl-1 antikoerper, fb72f02 antikoerper, wu:fb70a08 antikoerper, wu:fb72f02 antikoerper, zfMLP1 antikoerper, zfMcl-1a antikoerper, zgc:109835 antikoerper, zgc:109763 antikoerper, E3 antikoerper, E3-2 antikoerper, RNE3 antikoerper, RNU107 antikoerper, SNORA63A antikoerper, elF-4AII antikoerper, MCL1, BCL2 family apoptosis regulator antikoerper, myeloid cell leukemia sequence 1 antikoerper, MCL1, BCL2 family apoptosis regulator a antikoerper, MCL1, BCL2 family apoptosis regulator b antikoerper, small nucleolar RNA, H/ACA box 63 antikoerper, MCL1 antikoerper, Mcl1 antikoerper, mcl1a antikoerper, mcl1b antikoerper, SNORA63 antikoerper
Hintergrund
Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types. Mcl-1 is essential for embryogenesis (5) and for the development and maintenance of B and T lymphocytes in animals. Mcl-1 exists as at least two distinct isoforms designated Mcl-1L and Mcl-1S. In marked contrast to the larger isoform of Mcl-1, overexpression of Mcl-1S promotes cell death.Synonyms: BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein, EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, r004
Gen-ID
4170
NCBI Accession
NP_001184249
Pathways
MAPK Signalweg
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