Retinoblastoma Binding Protein 8 Antikörper (Center)

Produktnummer ABIN783608

Der Kaninchen Polyklonal Anti-Retinoblastoma Binding Protein 8-Antikörper wurde für WB und EIA validiert. Er ist geeignet, Retinoblastoma Binding Protein 8 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Retinoblastoma Binding Protein 8 Antikörper (Center) (ABIN783608)

Target: Retinoblastoma Binding Protein 8 (RBBP8)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Retinoblastoma Binding Protein 8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Retinoblastoma Binding Protein 8 Antikörper

Bindungsspezifität: Center

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the center of human RBBP8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu Retinoblastoma Binding Protein 8

Target: Retinoblastoma Binding Protein 8 (RBBP8)

Andere Bezeichnung: RBBP8

Hintergrund: RBBP8, also known as CtBP (carboxy-terminal binding protein) interacting protein (CTIP), was characterized for its role in transcription as a cofactor for the transcriptional repressor CtBP, and also as a binding partner for other proteins including the cell cycle regulators retinoblastoma protein (Rb) and breast cancer 1 (BRCA1). It is ubiquitously expressed and localizes to the nucleus. RBBP8 is thought to modulate the functions in cell proliferation, transcriptional regulation and DNA repair. RBBP8 also plays a central role in the cell cycle checkpoint response to DNA double-stranded breaks (DSBs), with new evidence demonstrating that it controls the choice of DSB repair pathway.Synonyms: CTIP, CtBP-interacting protein, RBBP-8, Retinoblastoma-binding protein 8, Retinoblastoma-interacting protein and myosin-like

Gen-ID: 5932

NCBI Accession: NP_002885

UniProt: Q99708

Pathways: Zellzyklus, DNA Reparatur