ANAPC10 Antikörper (Center)
-
- Target Alle ANAPC10 Antikörper anzeigen
- ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))
-
Bindungsspezifität
- Center
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ANAPC10 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- 16 amino acid peptide near the center of human APC10
- Top Product
- Discover our top product ANAPC10 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody (in aliquots) at -20 °C.
-
- Target
- ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))
- Andere Bezeichnung
- APC10 / ANAPC10 (ANAPC10 Produkte)
- Synonyme
- APC10 antikoerper, DOC1 antikoerper, 1500026N15Rik antikoerper, A830003M23Rik antikoerper, CG11419 antikoerper, Dmel\\CG11419 antikoerper, ANAPC10 antikoerper, SPBC1E8.06 antikoerper, anapc10 antikoerper, MGC85037 antikoerper, DDBDRAFT_0202332 antikoerper, DDBDRAFT_0235160 antikoerper, DDB_0202332 antikoerper, DDB_0235160 antikoerper, anaphase promoting complex subunit 10 antikoerper, Anaphase Promoting Complex subunit 10 antikoerper, anaphase promoting complex subunit DOC1 antikoerper, anaphase-promoting complex subunit Apc10 antikoerper, anaphase promoting complex subunit antikoerper, predicted protein antikoerper, anaphase promoting complex subunit 10 S homeolog antikoerper, ANAPC10 antikoerper, Anapc10 antikoerper, APC10 antikoerper, DOC1 antikoerper, apc10 antikoerper, CAALFM_C107850CA antikoerper, anapc10 antikoerper, LOC692856 antikoerper, anapc10.S antikoerper, NAEGRDRAFT_66759 antikoerper
- Hintergrund
- Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC10 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. It has been suggested that APC10 plays a role to regulate the binding of specific substrates to the APC/C complex, similar to that of coactivators.Synonyms: Anaphase-promoting complex subunit 10, Cyclosome subunit 10
- Gen-ID
- 10393
- NCBI Accession
- NP_055700
- UniProt
- Q9UM13
- Pathways
- M Phase
-