STEAP4 Antikörper (Center)

Produktnummer ABIN783554

Der Kaninchen Polyklonal anti-STEAP4 Antikörper wird verwendet zum Nachweis von STEAP4 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und EIA.

Kurzübersicht für STEAP4 Antikörper (Center) (ABIN783554)

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-STEAP4 Antikörper

Bindungsspezifität: Center

Spezifität: This antibody detects STEAP4 at Center.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide from near the center of human STEAP4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu STEAP4

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Andere Bezeichnung: STEAP4

Hintergrund: The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression. At least two isoforms are known to exist for this protein. This STEAP4 antibody does not cross-react with other STEAP proteins.Synonyms: Metalloreductase STEAP4, STAMP2, STEAP-4, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2, TNFAIP9, Tumor necrosis factor, alpha-induced protein 9

Gen-ID: 79689

NCBI Accession: NP_078912

UniProt: Q687X5

Pathways: Transition Metal Ion Homeostasis