STEAP4 Antikörper (AA 1-100)

Produktnummer ABIN7270588

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch STEAP4 in WB und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für STEAP4 Antikörper (AA 1-100) (ABIN7270588)

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-STEAP4 Antikörper

Bindungsspezifität: AA 1-100

Verwendungszweck: STEAP4 Rabbit pAb

Sequenz: MEKTCIDALP LTMNSSEKQE TVCIFGTGDF GRSLGLKMLQ CGYSVVFGSR NPQKTTLLPS GAEVLSYSEA AKKSGIIIIA IHREHYDFLT ELTEVLNGKI

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human STEAP4 (NP_001192245).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu STEAP4

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Andere Bezeichnung: STEAP4

Hintergrund: The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011],STAMP2,SchLAH,TIARP,TNFAIP9,STEAP4,Cancer,Tumor immunology,Tumor-associated antigens,Tumor biomarkers,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,STEAP4

Molekulargewicht: 31kDa/51kDa

Gen-ID: 79689

UniProt: Q687X5

Pathways: Transition Metal Ion Homeostasis