STEAP4 Antikörper (AA 180-260)

Produktnummer ABIN7225090

Der Kaninchen Polyklonal anti-STEAP4 Antikörper wird verwendet zum Nachweis von STEAP4 in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, IHC und IF.

Kurzübersicht für STEAP4 Antikörper (AA 180-260) (ABIN7225090)

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-STEAP4 Antikörper

Bindungsspezifität: AA 180-260

Verwendungszweck: Rabbit Anti-STAMP2 Polyclonal Antibody

Spezifität: STAMP2 Polyclonal Antibody detects endogenous levels of STAMP2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human STAMP2 at AA range: 180-260

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu STEAP4

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Andere Bezeichnung: STAMP2

Hintergrund: STEAP4, STAMP2, TNFAIP9, Metalloreductase STEAP4, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2, Tumor necrosis factor, alpha-induced protein 9The protein encoded by STEAP4 (STEAP4 metalloreductase)belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that STEAP4 maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for STEAP4.

Gen-ID: 79689

UniProt: Q687X5

Pathways: Transition Metal Ion Homeostasis