PKM2 Antikörper
Kurzübersicht für PKM2 Antikörper (ABIN781224)
Target
Alle PKM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Protein G-Sepharose affinity purified.
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Immunogen
- Recombinant fragment of Human PKM2 (N-terminus).
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 50µg/50µl
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Buffer
- 0.02% Sodium Azide, 50% glycerol, 1% BSA, PBS, PH7.4.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- PKM2 (Pyruvate Kinase M2 (PKM2))
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Andere Bezeichnung
- PKM2
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Hintergrund
- PKM2 (pyruvate kinase, muscle) catalyzes the production of phosphoenol pyruvate from pyruvate and ATP. PKM2 has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. It has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
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Molekulargewicht
- 45kDa
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NCBI Accession
- NM_182471
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Pathways
- Warburg Effekt
Target
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