Tyrosinase-Related Protein 1 Antikörper (Cleaved-Asn126)

Produktnummer ABIN8125497

Der Kaninchen Polyklonal anti-Tyrosinase-Related Protein 1 Antikörper wird verwendet zum Nachweis von Tyrosinase-Related Protein 1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für Tyrosinase-Related Protein 1 Antikörper (Cleaved-Asn126) (ABIN8125497)

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tyrosinase-Related Protein 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Tyrosinase-Related Protein 1 Antikörper

Bindungsspezifität: Cleaved-Asn126

Verwendungszweck: CATB (Cleaved-Asn126) Antibody

Spezifität: This antibody detects endogenous levels of Human CATB (Cleaved-Asn126, protein was cleaved amino acid sequence between 126-127 )

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human CATB (Cleaved-Asn126)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-2000 ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Andere Bezeichnung: CATB

Hintergrund:

Synonyms: Cathepsin B (EC 3.4.22.1, APP secretase, APPS, Cathepsin B1) [Cleaved into: Cathepsin B light chain, Cathepsin B heavy chain]

Background: catalytic activity:Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.,function:Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.,similarity:Belongs to the peptidase C1 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Dimer of a heavy chain and a light chain cross-linked by a disulfide bond.,

Gene Name: CTSB CPSB

Protein Name: CATB (Cleaved-Asn126)

Gen-ID: 1508

UniProt: P07858