SQSTM1 Antikörper
Kurzübersicht für SQSTM1 Antikörper (ABIN8124591)
Target
Alle SQSTM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- SQSTM1/p62 Antibody
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Spezifität
- This antibody detects endogenous levels of SQSTM at Human/Mouse/Rat
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from human SQSTM
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000, IF ICC 1:100-500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- SQSTM1 (Sequestosome 1 (SQSTM1))
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Andere Bezeichnung
- SQSTM1/p62
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Hintergrund
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Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009],
Gene Name: SQSTM1 ORCA OSIL
Protein Name: SQSTM
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Gen-ID
- 8878
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UniProt
- Q13501
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Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
Target
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